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1.
J Biosci ; 2001 Nov; 26(4 Suppl): 391-405
Article in English | IMSEAR | ID: sea-111033

ABSTRACT

Approximately 48.2% of couples of 15 to 49 years of age practice family planning methods in India. Female sterilization accounts for 34.2%, with male sterilization declining from 3.4% in 1992-93 to 1.9% in 1998-99. Use of the condom increased to 3.1% from 2.4%. There is an urgent need for research to develop new contraceptive modalities especially for men and also for women and to make existing methods more safe, affordable and acceptable. Current efforts in India to develop a male contraceptive are mainly directed towards (i) development of antispermatogenic agents to suppress sperm production, (ii) prevention of sperm maturation, (iii) prevention of sperm transport through vas deferens or rendering these sperm infertile and (iv) prevention of sperm deposition. Research work in the field of prevention of sperm transport through vas deferens has made significant advances. Styrene maleic anhydride (SMA) disturbed the electrical charge of spermatozoa leading to acrosome rupture and consequent loss in fertilizing ability of sperm. A multicentre phase-III clinical trial using SMA is continuing and it is hoped that the SMA approach would be available in the near future as an indigenously developed injectable intra-vasal male contraceptive. The safety and efficacy of available oral contraceptives were evaluated. An indigenously developed oral contraceptive 'Centchorman', which is a nonsteroidal, weakly estrogenic but potently antiestrogenic, was found to be safe and effective and is now being marketed in India since 1991 as a 'once a week' pill. Cyclofem and Mesigyna have been recommended as injectable contraceptives with proper counselling and service delivery by Indian studies. It has been recommended that these injectable contraceptives be added to the existing range of contraceptive methods available in the National Family Planning Programme. Based on the Indian studies CuT 200 was also recommended. Studies have indicated the advantage of intrauterine devices (IUD); they are long acting, relatively easily removed and fertility returns rapidly after their removal. Recent studies have recommended CuT 200 for use up to 5 years. The combination of some plant products i.e. Embelia ribes, Borax and Piper longum has been found to be safe and effective as a female contraceptive and the results of phase-I clinical trials are encouraging. Research work is going on in the country in various areas with special reference to hormonal contraceptive - a three monthly injectable contraceptive, immuno-contraceptives, antiprogestins, etc.


Subject(s)
Animals , Clinical Trials as Topic , Contraception/methods , Contraceptive Agents, Female/administration & dosage , Contraceptive Agents, Male/administration & dosage , Contraceptive Devices, Female/statistics & numerical data , Contraceptive Devices, Male/statistics & numerical data , Female , Hormone Antagonists/administration & dosage , Humans , India , Male , Norgestrel/administration & dosage , Plant Extracts/administration & dosage , Plants, Medicinal , Pregnancy , Vaccines, Conjugate/administration & dosage
2.
Med. & soc ; 21(4): 183-93, oct.-dic. 1998. tab
Article in Spanish | LILACS | ID: lil-254890

ABSTRACT

Objetivo: analizar los conocimientos, actitudes y conductas de los adolescentes en relación con el preservativo. Población: adolescentes escolarizados de la ciudad de Buenos Aires, entre 15 y 18 años. Muestra: aleatoria representativa de escuelas, integrada por 952 adolescentes. Métodos: cuestionario autoadministrado de 72 preguntas. Análisis uni y bivariado de datos. Resultados: el preservativo aparece como el método anticonceptivo más reconocido entre los adolescentes estudiados. Si bien la difusión acerca del papel preventivo del preservativo frente al SIDA, ha crecido en los últimos años, es preocupante el alto porcentaje de adolescentes que no saben cómo usarlo y que no lo usan en su debut sexual y en su vida sexual posterior. Las mujeres, que tienen que vencer más barreras culturales, aparecen más desprotegidas, tanto frente a un embarazo no planeado como frente al riesgo de una enfermedad como el SIDA. Y lo mismo ocurre con los hijos de padres menos educados


Subject(s)
Humans , Adolescent , Contraception Behavior/statistics & numerical data , Contraceptive Devices, Male/statistics & numerical data , Pregnancy in Adolescence , Sexual Behavior , Sexuality , Acquired Immunodeficiency Syndrome/prevention & control , Argentina
3.
Rev. argent. cir ; 66(1/2): 26-32, ene.-feb. 1994. ilus
Article in Spanish | LILACS | ID: lil-136600

ABSTRACT

Presentamos un trabajo de investigación clínica de protección de anastomosis colo-colónica, colo-rectal, y colo-anal, con la colocación endoluminal de un preservativo que se fija al cabo proximal y se desliza al cabo distal para proteger el sitio anastomótico durante los primeros 10 o 15 días, impidiendo durante ese tiempo el contacto de la materia fecal con la línea de sutura. Cumplido dicho plazo el preservativo se elimina espontáneamente por el ano. Colocamos el protector en 39 anastomosis: 12 colo-cólicas, 25 colo-rectales y 2 colo-anales, sin morbi-mortalidad. En el 90 por ciento las cirugías fueron programadas y en el 10 por ciento restante de urgencia


Subject(s)
Humans , Male , Female , Middle Aged , Anastomosis, Surgical/methods , Colonic Neoplasms/surgery , Contraceptive Devices, Male/statistics & numerical data , Rectal Neoplasms/surgery , Anastomosis, Surgical/classification , Anastomosis, Surgical/adverse effects , Diverticulitis, Colonic/surgery , Prostheses and Implants/trends , Suture Techniques/instrumentation , Suture Techniques/standards
6.
Southeast Asian J Trop Med Public Health ; 1990 Sep; 21(3): 447-52
Article in English | IMSEAR | ID: sea-34819

ABSTRACT

A survey of 15-34 year old men in Mae Sot, Tak, was conducted in December 1989 to determine their knowledge about AIDS, HIV transmission, and sexual behavior to guide future AIDS prevention programs. A total of 172 men from the municipality (urban) and 311 men from the surrounding villages (rural) were interviewed. More than 90% of both groups possessed knowledge about the existing modes of HIV transmission, however, there were some who had the mistaken belief that AIDS can be spread by mosquito bites, using public toilets, or through various forms of casual contact. These misconceptions in the community underscore the need for more education designed to counteract them. Although nearly all of them knew that condoms can prevent infection, only half of the urban and one-third of the rural sexually active men had ever used a condom during their sexual intercourse with prostitutes. However, condom use increased over time. Since a number of these men first engaged in sexual intercourse at an early age, the promotion of health education about AIDS in the schools is essential.


Subject(s)
Acquired Immunodeficiency Syndrome/prevention & control , Adolescent , Adult , Contraceptive Devices, Male/statistics & numerical data , Female , HIV Infections/prevention & control , Health Education , Health Knowledge, Attitudes, Practice , Health Surveys , Humans , Male , Sex Work , Rural Health , Sexual Behavior , Socioeconomic Factors , Thailand , Urban Health
7.
Southeast Asian J Trop Med Public Health ; 1990 Sep; 21(3): 453-7
Article in English | IMSEAR | ID: sea-33768

ABSTRACT

A study was conducted to determine the effect of preventive educational efforts among 621 female prostitutes in Mae Sot, Tak Province, in 1989. The intensive health education program at a personal level and free condom distribution to the prostitutes began in March and June 1989, respectively. The proportion of prostitutes' sexual partners using condoms increased from 13.5% in January 1989 to 50.4% by December 1989. The reported increase in condom use was supported by the decline in the incidence rate of gonorrhea among the prostitutes during the same period. Anal intercourse was not commonly practised in these women and decreased from 9.7% in January to 1.8% in December 1989. None of the prostitutes interviewed throughout the year reported using intravenous drugs, nor reported having a steady sexual partner who was an intravenous drug user. None out of 248 prostitutes tested in January 1989 were HIV-1 seropositive. After that throughout the year, 15 of 373 (4.0%) additional prostitutes in this area were found to be seropositive on their first test. Ten out of 405 (2.5%) initially-seronegative prostitutes who were subsequently tested at 3-month intervals became seropositive. The effect of health education and condom promotion among our study prostitutes was modest. Similar studies are needed to evaluate the programs in other settings of Thailand, particularly in areas with high prevalence of HIV-1 infection.


Subject(s)
Adolescent , Adult , Contraceptive Devices, Male/statistics & numerical data , Female , Gonorrhea/epidemiology , HIV Infections/transmission , Health Education , Health Promotion , Humans , Sex Work , Sexual Behavior , Sexual Partners , Socioeconomic Factors , Thailand
8.
Southeast Asian J Trop Med Public Health ; 1990 Jun; 21(2): 301-5
Article in English | IMSEAR | ID: sea-33220

ABSTRACT

A study of female prostitutes in Manila who tested positive for human immunodeficiency virus (HIV) antibody ascertained demographic and sexual behavior information following diagnosis. Counselling alone did not appear to have a major impact on the sexual behavior of the HIV positive women since most continued to work as prostitutes. Switching from high risk to low risk jobs in bars is not effective in preventing HIV positive women from engaging in prostitution. Revoking work permits is only effective if enforced with adequate follow up. Alternative job training programs may offer a viable approach.


Subject(s)
Contraceptive Devices, Male/statistics & numerical data , Counseling/standards , Female , HIV Seropositivity/epidemiology , Health Education/standards , Humans , Philippines/epidemiology , Sex Work/legislation & jurisprudence , Surveys and Questionnaires , Sexual Behavior
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